我国科学家团队在《细胞》（Cell）杂志发表突破性成果，首次实现小鼠全身高清全景成像，单根神经纤维的细节清晰可辨。生物体内，亿万周围神经纤维构成精密的“生命物联网”，承载大脑与器官的双向通讯，调控运动、感觉及内脏功能。此前，因成像技术局限，神经纤维的精细网络难以完整解析。此次突破依托先进成像技术，突破分辨率瓶颈，使神经纤维的分布、连接与交互直观呈现。该成果为解析神经调控网络、探究神经疾病（如损伤、退行性病变）机理提供全新工具，有望推动神经科学跨越式发展，为疾病治疗靶点挖掘与干预策略开发奠定基础。
Chinese scientists have achieved a groundbreaking feat, as published in Cell: the first high - resolution panoramic imaging of a mouse, where even single nerve fibers are visible in exquisite detail. In living organisms, billions of peripheral nerve fibers form a sophisticated "life Internet of Things," mediating bidirectional communication between the brain and organs, and regulating movement, sensation, and visceral functions. Previously, technological limitations hindered the full visualization of their intricate networks. This breakthrough leverages advanced imaging techniques to overcome resolution barriers, revealing the distribution, connections, and interactions of nerve fibers vividly. It provides a novel tool for decoding neural regulatory networks and investigating mechanisms of neurological diseases (e.g., injury, degeneration), promising to advance neuroscience dramatically and lay a foundation for discovering therapeutic targets and developing intervention strategies.
